PACAP 27

£175.00 1mg

SKU: PA-010 Categories: ,

Endogenous PAC1 receptor agonist.

PACAP 27 is an endogenous neuropeptide and is the C-terminally truncated form of PACAP 38. PACAP 27 has considerable homology with vasoactive intestinal peptide (VIP) but is >100 fold more potent than VIP as an agonist of the PAC1 receptor. PACAP 27 functions in the control of anterior pituitary hormone secretion, vasodilation, adrenaline secretion, insulin secretion and immunosuppression.

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Additional information

Other Names

PACAP 1-27, Pituitary Adenylate Cyclase-Activating Polypeptide 1-27, PACAP-38 (1-27) amide (human, mouse, ovine, porcine, rat)

Three Letter Sequence

H-His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-NH2

Molecular Weight

3147.65

Molecular Formula

C142H224N40O39S

Sequence

HSDGIFTDSYSRYRKQMAVKKYLAAVL-NH2

Solubility

Soluble to 1 mg/ml in water

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Modifications

C terminal amide

Searchable Words

PACAP-27, PACAP27, 127317-03-7, PACAP 1-27, Pituitary Adenylate Cyclase-Activating Polypeptide 1-27, HSDGIFTDSYSRYRKQMAVKKYLAAVL, PA-010, PA010