p13

£125.00 1mg

GPR133 activator.

p13 is a peptide derived from the C-terminal component which starts at the GPCR proteolysis cleavage site of GPR133. p13 specifically activates both generated chimeric P2Y12-CTF(GPR133) receptors and the wild-type GPR133 ?receptor and is an agonist as measured by cAMP accumulation. p13 is highly selective for GPR133, and is a short tethered sequence (the Stachel sequence) within the ectodomain of GPR133, reinforcing that tethered peptide activation is a common signalling modality for the adhesion GPCR class of receptors.

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SKU: AC-010 Categories: ,

Additional information

Three Letter Sequence

H-Thr-His-Phe-Gly-Val-Leu-Met-Asp-Leu-Pro-Arg-Ser-Ala-OH

Molecular Weight

1442.73

Molecular Formula

C64H102N18O18S

Sequence

THFGVLMDLPRSA

Solubility

Soluble in water

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Searchable Words

THFGVLMDLPRSA, p13, AC-010, AC010, Stachel sequence