Orexin B (Human)
£175.00 1mg
Endogenous agonist at OX1 and OX2 receptors.
Orexin B (human) is an endogenous agonist peptide at orexin receptors with some selectivity for OX2 (with Ki values of 420 and 36 nM for OX1 and OX2 receptors respectively). Orexin B (human) stimulates feeding following central administration and may be involved in the control of sleep-wake cycle and other hypothalamic functions. Orexin B (human) is neuroprotective for dopaminergic neurons in animal models.
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Additional information
| Three Letter Sequence | H-Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2 |
|---|---|
| Molecular Weight | 2899.37 |
| Molecular Formula | C123H212N44O35S |
| Sequence | RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2 |
| Solubility | Soluble to 1 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| Purity | >95% by HPLC |
| Modifications | C terminal amide |
| Searchable Words | Orexin B (human), 205640-91-1, RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2, RSGPPGLQGRLQRLLQASGNHAAGILTM, OX-020, OX020 |