Orexin B (human)
£175.00 1mg
Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.
Endogenous agonist at OX1 and OX2 receptors.
Orexin B (human) is an endogenous agonist peptide at orexin receptors with some selectivity for OX2 (with Ki values of 420 and 36 nM for OX1 and OX2 receptors respectively). Orexin B (human) stimulates feeding following central administration and may be involved in the control of sleep-wake cycle and other hypothalamic functions. Orexin B (human) is neuroprotective for dopaminergic neurons in animal models.
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Additional information
| Three Letter Sequence | H-Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2 |
|---|---|
| Molecular Weight | 2899.37 |
| Molecular Formula | C123H212N44O35S |
| Sequence | RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2 |
| Solubility | Soluble to 1 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| Purity | >95% by HPLC |
| Modifications | C terminal amide |
| Searchable Words | Orexin B (human), 205640-91-1, RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2, RSGPPGLQGRLQRLLQASGNHAAGILTM, OX-020, OX020 |