Orexin B (Human)

£175.00 1mg

Endogenous agonist at OX1 and OX2 receptors.

Orexin B (human) is an endogenous agonist peptide at orexin receptors with some selectivity for OX2 (with Ki values of 420 and 36 nM for OX1 and OX2 receptors respectively). Orexin B (human) stimulates feeding following central administration and may be involved in the control of sleep-wake cycle and other hypothalamic functions. Orexin B (human) is neuroprotective for dopaminergic neurons in animal models.

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SKU: OX-020 Categories: ,

Additional information

Three Letter Sequence

H-Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2

Molecular Weight

2899.37

Molecular Formula

C123H212N44O35S

Sequence

RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2

Solubility

Soluble to 1 mg/ml in water

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Modifications

C terminal amide

Searchable Words

Orexin B (human), 205640-91-1, RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2, RSGPPGLQGRLQRLLQASGNHAAGILTM, OX-020, OX020