Obestatin (Rat)
£55.00 1mg
Hormone which can suppress food intake.
Similarly to ghrelin, obestatin is derived from the proteolytic cleavage of proghrelin and binds to the orphan G protein-coupled receptor GPR39 to suppress food intake, inhibit jejunal contraction and decrease body-weight gain in rats, contrary to the appetite-stimulating effects of ghrelin. Thus two peptide hormones with opposing action in weight regulation are derived from the same ghrelin gene.
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Additional information
| Three Letter Sequence | H-Phe-Asn-Ala-Pro-Phe-Asp-Val-Gly-Ile-Lys-Leu-Ser-Gly-Ala-Gln-Tyr-Gln-Gln-His-Gly-Arg-Ala-Leu-NH2 |
|---|---|
| Molecular Weight | 2516.8 |
| Molecular Formula | C114H174N34O31 |
| Sequence | FNAPFDVGIKLSGAQYQQHGRAL-NH2 |
| Solubility | Soluble in dilute acid |
| Appearance | Freeze dried solid |
| Storage | Store dessicated and frozen in the dark |
| Purity | >95% by HPLC |
| Modifications | C terminal amide |
| Searchable Words | H-FNAPFDVGIKLSGAQYQQHGRAL-NH2, FNAPFDVGIKLSGAQYQQHGRAL-NH2, 869705-22-6, obestatin, proghrelin, orphan G protein-coupled receptor, GPR39 , hormone, GH-130, GH130 |