NSC 632839
£65.00 10mg
Ubiquitin isopeptidase inhibitor.
NSC 632839, also known as F6, targets the ubiquitin-proteasome system by inhibiting ubiquitin isopeptidases. NSC 632839 is able to activate an apoptosome-independent apoptotic pathway which includes a Bcl-2-dependent but apoptosome-independent mitochondrial pathway with up-regulation of the BH3-only protein Noxa, stabilization of the inhibitor of apoptosis antagonist Smac, and also the involvement of the death receptor pathway.
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Additional information
| Other Names | F6 |
|---|---|
| Three Letter Sequence | 3,5-Bis[(4-methylphenyl)methylene]-4-piperidone hydrochloride |
| Molecular Weight | 339.86 |
| Molecular Formula | C21H21NO.HCl |
| Sequence | 3,5-Bis[(4-methylphenyl)methylene]-4-piperidone hydrochloride |
| Solubility | Soluble in water |
| Appearance | White solid |
| Storage | Stotre, dry, frozen and in the dark |
| Purity | >98% by TLC |