NSC 632839

£65.00 10mg

Ubiquitin isopeptidase inhibitor.

NSC 632839, also known as F6, targets the ubiquitin-proteasome system by inhibiting ubiquitin isopeptidases. NSC 632839 is able to activate an apoptosome-independent apoptotic pathway which includes a Bcl-2-dependent but apoptosome-independent mitochondrial pathway with up-regulation of the BH3-only protein Noxa, stabilization of the inhibitor of apoptosis antagonist Smac, and also the involvement of the death receptor pathway.

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SKU: PI-080 Categories: ,

Additional information

Other Names

F6

Three Letter Sequence

3,5-Bis[(4-methylphenyl)methylene]-4-piperidone hydrochloride

Molecular Weight

339.86

Molecular Formula

C21H21NO.HCl

Sequence

3,5-Bis[(4-methylphenyl)methylene]-4-piperidone hydrochloride

Solubility

Soluble in water

Appearance

White solid

Storage

Stotre, dry, frozen and in the dark

Purity

>98% by TLC