NSC 405020

£75.00 10mg

MMP14 inhibitor.

NSC 405020 is a matrix metalloproteinase inhibitor that targets the hemopexin domain (PEX) of membrane type-1 matrix metalloproteinase (MT1-MMP, also known as MMP 14). The hemopexin domain is distinct from and additional to the catalytic domain and inhibition with NSC 405020 affects PEX and the ability of MT1-MMP to function properly to degrade COL-I to support tumour cell invasion. Intratumoral injections of NSC 405020 significantly repress tumour growth.

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SKU: PI-070 Categories: ,

Additional information

Three Letter Sequence

3,4-Dichloro-N-(1-methylbutyl)benzamide

Molecular Weight

260.16

Molecular Formula

C12H15Cl2NO

Sequence

3,4-Dichloro-N-(1-methylbutyl)benzamide

Solubility

Soluble in DMSO

Appearance

White solid

Storage

Store dry, dark and frozen

Purity

>98% by PHLC