Nafamostat Mesylate

£65.00 10mg

SKU: PI-040 Categories: ,

Serine protease inhibitor.

Nafamostat mesylate is a serine protease inhibitor. It inhibits a large number of Lys/Arg specific serine proteinases, and is also a tryptase inhibitor. In vivo nafamostat is a fast-acting proteolytic inhibitor and used during hemodialysis to prevent the proteolysis of fibrinogen into fibrin. Nafamostat also has some antiviral and anti-cancer properties and has been identified as a potential treatment for COVID-19.

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Additional information

Three Letter Sequence

4-[(Aminoiminomethyl)amino]benzoic acid 6-(aminoiminomethyl)-2-naphthalenyl ester dimethanesulfonate

Molecular Weight

539.59

Molecular Formula

C19H17N5O2.2CH4O3S

Sequence

4-[(Aminoiminomethyl)amino]benzoic acid 6-(aminoiminomethyl)-2-naphthalenyl ester dimethanesulfonate

Solubility

Soluble to 100 mM in water

Appearance

White solid

Storage

Store desiccated, frozen and in the dark

Purity

>98% by HPLC