MOG (35-55) (rat)
£85.00 1mg
Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.
Highly encephalitogenic fragment of myelin oligodendrocyte glycoprotein.
MOG (35-55) (rat) is a fragment of myelin oligodendrocyte glycoprotein (MOG), a transmembrane glycoprotein expressed at the surface of oligodendrocyte cells and on the outermost surface of the myelin sheath. MOG (35-55) (rat) is highly encephalitogenic, inducing strong T-cell and B-cell responses. As MOG (35-55) (rat) injection produces relapsing-remitting neurologic disease with clinical, histopathologic and immune similarities to multiple sclerosis, MOG induced demyelination is used as a model for MS research.
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Additional information
| Three Letter Sequence | H-Met-Glu-Val-Gly-Trp-Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys-OH |
|---|---|
| Molecular Weight | 2582 |
| Molecular Formula | C118H177N35O29S |
| Sequence | MEVGWYRSPFSRVVHLYRNGK |
| Solubility | Soluble in dilute acid |
| Appearance | Freeze dried solid |
| Storage | Store dark, frozen and desiccated |
| Purity | >95% by HPLC |
| Searchable Words | MOG (35-55) (rat), myelin oligodendrocyte glycoprotein, MOG, encephalitogenic, multiple sclerosis, demyelination, MS, H-MEVGWYRSPFSRVVHLYRNGK-OH, MEVGWYRSPFSRVVHLYRNGK, 149635-73-4, NR-020, NR020 |