MOG (35-55) (Rat)
£85.00 1mg
Highly encephalitogenic fragment of myelin oligodendrocyte glycoprotein.
MOG (35-55) (rat) is a fragment of myelin oligodendrocyte glycoprotein (MOG), a transmembrane glycoprotein expressed at the surface of oligodendrocyte cells and on the outermost surface of the myelin sheath. MOG (35-55) (rat) is highly encephalitogenic, inducing strong T-cell and B-cell responses. As MOG (35-55) (rat) injection produces relapsing-remitting neurologic disease with clinical, histopathologic and immune similarities to multiple sclerosis, MOG induced demyelination is used as a model for MS research.
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Additional information
| Three Letter Sequence | H-Met-Glu-Val-Gly-Trp-Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys-OH |
|---|---|
| Molecular Weight | 2582 |
| Molecular Formula | C118H177N35O29S |
| Sequence | MEVGWYRSPFSRVVHLYRNGK |
| Solubility | Soluble in dilute acid |
| Appearance | Freeze dried solid |
| Storage | Store dark, frozen and desiccated |
| Purity | >95% by HPLC |
| Searchable Words | MOG (35-55) (rat), myelin oligodendrocyte glycoprotein, MOG, encephalitogenic, multiple sclerosis, demyelination, MS, H-MEVGWYRSPFSRVVHLYRNGK-OH, MEVGWYRSPFSRVVHLYRNGK, 149635-73-4, NR-020, NR020 |