MOG (35-55) (Human)
£85.00 1mg
Fragment of human myelin oligodendrocyte glycoprotein (MOG).
MOG (35-55) (human) is a truncated fragment of human myelin oligodendrocyte glycoprotein (MOG), the transmembrane glycoprotein expressed at the surface of oligodendrocyte cells and on the outermost surface of the myelin sheath, which can be used for the induction of experimental autoimmune encephalomyelitis in mouse and rat models. In contrast to MOG (35-55) (rat), Mog (35-55) (human) is only weakly encephalitogenic but both induce antibodies that are equivalent in titer and IgG subclass, demonstrating that EAE can be induced in C57BL/6 mice by two different mechanisms.
Please contact us for availability.
Please contact us for availability.
Additional information
| Three Letter Sequence | H-Met-Glu-Val-Gly-Trp-Tyr-Arg-Pro-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys-OH |
|---|---|
| Molecular Weight | 2592 |
| Molecular Formula | C120H179N35O28S |
| Sequence | MEVGWYRPPFSRVVHLYRNGK |
| Solubility | Soluble in dilute acid |
| Appearance | Freeze dried solid |
| Storage | Store dark, frozen and desiccated |
| Purity | >95% by HPLC |
| Searchable Words | MOG (35-55) (human), human myelin oligodendrocyte glycoprotein, MOG, myelin sheath, experimental autoimmune encephalomyelitis, encephalitogenic, EAE, 163158-19-8, H-MEVGWYRPPFSRVVHLYRNGK-OH, MEVGWYRPPFSRVVHLYRNGK, NR-010, NR010 |