MOG (35-55) (Human)

£85.00 1mg

Fragment of human myelin oligodendrocyte glycoprotein (MOG).

MOG (35-55) (human) is a truncated fragment of human myelin oligodendrocyte glycoprotein (MOG), the transmembrane glycoprotein expressed at the surface of oligodendrocyte cells and on the outermost surface of the myelin sheath, which can be used for the induction of experimental autoimmune encephalomyelitis in mouse and rat models. In contrast to MOG (35-55) (rat), Mog (35-55) (human) is only weakly encephalitogenic but both induce antibodies that are equivalent in titer and IgG subclass, demonstrating that EAE can be induced in C57BL/6 mice by two different mechanisms.

Please contact us for availability.

Please contact us for availability.

SKU: NR-010 Categories: ,

Additional information

Three Letter Sequence

H-Met-Glu-Val-Gly-Trp-Tyr-Arg-Pro-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys-OH

Molecular Weight

2592

Molecular Formula

C120H179N35O28S

Sequence

MEVGWYRPPFSRVVHLYRNGK

Solubility

Soluble in dilute acid

Appearance

Freeze dried solid

Storage

Store dark, frozen and desiccated

Purity

>95% by HPLC

Searchable Words

MOG (35-55) (human), human myelin oligodendrocyte glycoprotein, MOG, myelin sheath, experimental autoimmune encephalomyelitis, encephalitogenic, EAE, 163158-19-8, H-MEVGWYRPPFSRVVHLYRNGK-OH, MEVGWYRPPFSRVVHLYRNGK, NR-010, NR010