MLCK Inhibitor Peptide 18
£65.00 1mg
Selective inhibitor of myosin light chain kinase.
MLCK inhibitor peptide 18 is a selective cell permeable inhibitor of myosin light chain kinase with an IC50 of 50 nM. MLCK inhibitor peptide 18 displays 4000-fold selectivity over CaM kinase II and does not inhibit PKA. In vitro and in vivo treatment with the MLCK inhibitor peptide 18 attenuates the increased epithelial monolayer permeability and occludin endocytosis caused by intestinal anoxia/reoxygenation (A/R) injury.
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Additional information
| Other Names | Myosin Light Chain Kinase Inhibitor Peptide 18, Peptide 18 |
|---|---|
| Three Letter Sequence | H-Arg-Lys-Lys-Tyr-Lys-Tyr-Arg-Arg-Lys-NH2 |
| Molecular Weight | 1324.64 |
| Molecular Formula | C60H105N23O11 |
| Sequence | RKKYKYRRK-NH2 |
| Solubility | Soluble to 1 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| Purity | >95% by HPLC |
| Modifications | C-terminal amide |
| Searchable Words | MLCK inhibitor peptide 18, 224579-74-2 |