Melanin concentrating hormone?(human, mouse, rat)
£175.00 1mg
Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.
Endogenous MCH agonist.
Melanin concentrating hormone (human, mouse, rat) is the endogenous agonist at melanin concentration hormone receptors, with IC50 values of 0.3 and 1.5 nM and EC50 values of 3.9 and 0.1 nM at MCH-R1 and MCH-R2 ?receptors respectively. Melanin concentrating hormone receptors are expressed in the central and peripheral nervous systems and melanin concentrating hormone plays an important role in the control of feeding, energy metabolism, body weight regulation, anxiety, sleep, and reward.
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Additional information
Other Names | MCH (human, mouse, rat) |
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Three Letter Sequence | H-Asp-Phe-Asp-Met-Leu-Arg-Cys*-Met-Leu-Gly-Arg-Val-Tyr-Arg-Pro-Cys*-Trp-Gln-Val-OH (disulfide bridge between cyteines 7 and 16) |
Molecular Weight | 2386.84 |
Molecular Formula | C105H160N30O26S4 |
Sequence | DFDMLRCMLGRVYRPCWQV |
Solubility | Soluble to 1 mg/ml in water |
Appearance | Freeze dried solid |
Storage | Store dry, frozen and in the dark |
Purity | >95% by HPLC |
Modifications | Disulfide bridge between cyteines 7 and 16 |
Searchable Words | MCH (human, mouse, rat), DFDMLRCMLGRVYRPCWQV, 128315-56-0, Melanin concentrating hormone (human, mouse, rat), MH-010, MH010 |