For both Human Platelet Lysate-XF (Xeno-Free) and Human Platelet Lysate-FD (Fibrinogen Depleted), a fibrinogen depletion step is obtained during the manufacturing process in order to remove all fibrins. In addition, heparins are added during the manufacturing process. This means that you do not need to add Heparin while preparing the cell culture mix.
For Human Platelet Lysate FD, the heparin used in manufacturing is derived from porcine intestine (and therefore not xeno-free).
For Human Platelet Lysate XF, the heparin used is a xeno-free version, and is fully synthetic, offering a fully xeno-free end product.