Magainin 1

£95.00 1mg

Broad spectrum antimicrobial.

Magainin 1 is a 23 amino acid amphipathic cationic peptide with broad-spectrum antimicrobial activities, originally extracted from the skin of the African clawed frog Xenopus laevis. Magainin 1 (and Magainin 2) are closely related hemolytic peptides which inhibit growth of bacteria by permeabilizing the cell membranes without significant toxicity against mammalian cells. The main target of magainin 1 and 2 is thought to be the lipid matrix of the membranes. Both magainin 1 and 2 are also cytotoxic to cancer cells and exhibit inhibitory action toward herpes simplex virus 1 and 2 (HSV 1 and 2).

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SKU: AM-100 Categories: ,

Additional information

Three Letter Sequence

H-Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Gly-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Lys-Ser-OH

Molecular Weight

2409.8

Molecular Formula

C112H177N29O28S

Sequence

GIGKFLHSAGKFGKAFVGEIMKS

Solubility

Soluble in dilute acid

Appearance

Freeze dried solid

Storage

Store frozen and desiccated in the dark

Purity

>95% by HPLC

Searchable Words

108433-99-4, H-GIGKFLHSAGKFGKAFVGEIMKS-OH, GIGKFLHSAGKFGKAFVGEIMKS, Magainin 1, amphipathic cationic peptide, antimicrobial, African clawed frog Xenopus laevis, hemolytic, haemolytic, inhibit growth of bacteria by permeabilizing the cell membranes, lipid matrix, membranes, cytotoxic, cancer, AM-100, AM100