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[Leu31,Pro34]-Neuropeptide Y (human, rat)

[Leu31,Pro34]-Neuropeptide Y (human, rat)

£175.00 1mg

SKU: NY-020 Categories: , ,

Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

Selective neuropeptide Y ?Y1 receptor agonist.

[Leu31,Pro34]-Neuropeptide Y (human, rat) is a high affinity neuropeptide Y Y1 receptor agonist with a Ki of 0.39 nM, and also some affinity for Y4 and Y5 receptors. [Leu31,Pro34]-NPY microinjected into the periaqueductal gray produces both analgesic and anxiolytic effects in rats, and intrathecal administration of [Leu31,Pro34]-Neuropeptide Y (human, rat) can attenuate itch behaviour in mice.

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Additional information

Other Names

[Leu31,Pro34]-NPY (human)
Three Letter Sequence

H-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Leu-Thr-Arg-Pro-Arg-Tyr-NH2
Molecular Weight

4241
Molecular Formula

C189H284N54O56S
Sequence

YPSKPDNPGEDAPAEDMARYYSALRHYINLLTRPRY-NH2
Solubility

Soluble to 1 mg/ml in water
Appearance

Freeze dried solid
Storage

Store dry, frozen and in the dark
Purity

>95% by HPLC
Modifications

C-terminal amide
Searchable Words

[Leu31,Pro34]-Neuropeptide Y (human, rat), [Leu31,Pro34]-NPY (human), 132699-73-1, YPSKPDNPGEDAPAEDMARYYSALRHYINLLTRPRY, YPSKPDNPGEDAPAEDMARYYSALRHYINLLTRPRY-NH2