[Leu31,Pro34]-Neuropeptide Y (Human, Rat)
£175.00 1mg
Selective neuropeptide Y ?Y1 receptor agonist.
[Leu31,Pro34]-Neuropeptide Y (human, rat) is a high affinity neuropeptide Y Y1 receptor agonist with a Ki of 0.39 nM, and also some affinity for Y4 and Y5 receptors. [Leu31,Pro34]-NPY microinjected into the periaqueductal gray produces both analgesic and anxiolytic effects in rats, and intrathecal administration of [Leu31,Pro34]-Neuropeptide Y (human, rat) can attenuate itch behaviour in mice.
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Additional information
| Other Names | [Leu31,Pro34]-NPY (human) |
|---|---|
| Three Letter Sequence | H-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Leu-Thr-Arg-Pro-Arg-Tyr-NH2 |
| Molecular Weight | 4241 |
| Molecular Formula | C189H284N54O56S |
| Sequence | YPSKPDNPGEDAPAEDMARYYSALRHYINLLTRPRY-NH2 |
| Solubility | Soluble to 1 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| Purity | >95% by HPLC |
| Modifications | C-terminal amide |
| Searchable Words | [Leu31,Pro34]-Neuropeptide Y (human, rat), [Leu31,Pro34]-NPY (human), 132699-73-1, YPSKPDNPGEDAPAEDMARYYSALRHYINLLTRPRY, YPSKPDNPGEDAPAEDMARYYSALRHYINLLTRPRY-NH2 |