[Leu31,Pro34]-Neuropeptide Y (Human, Rat)

£175.00 1mg

Selective neuropeptide Y ?Y1 receptor agonist.

[Leu31,Pro34]-Neuropeptide Y (human, rat) is a high affinity neuropeptide Y Y1 receptor agonist with a Ki of 0.39 nM, and also some affinity for Y4 and Y5 receptors. [Leu31,Pro34]-NPY microinjected into the periaqueductal gray produces both analgesic and anxiolytic effects in rats, and intrathecal administration of [Leu31,Pro34]-Neuropeptide Y (human, rat) can attenuate itch behaviour in mice.

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SKU: NY-020 Categories: ,

Additional information

Other Names

[Leu31,Pro34]-NPY (human)

Three Letter Sequence

H-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Leu-Thr-Arg-Pro-Arg-Tyr-NH2

Molecular Weight

4241

Molecular Formula

C189H284N54O56S

Sequence

YPSKPDNPGEDAPAEDMARYYSALRHYINLLTRPRY-NH2

Solubility

Soluble to 1 mg/ml in water

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Modifications

C-terminal amide

Searchable Words

[Leu31,Pro34]-Neuropeptide Y (human, rat), [Leu31,Pro34]-NPY (human), 132699-73-1, YPSKPDNPGEDAPAEDMARYYSALRHYINLLTRPRY, YPSKPDNPGEDAPAEDMARYYSALRHYINLLTRPRY-NH2