[Leu144, Arg147]-PLP (139-151)
£75.00 1mg
T cell receptor antagonist.
[Leu144, Arg147]-PLP (139-151) is an analogue of PLP (139-151) which can act as a T-cell receptor antagonist, able to prevent development of the autoimmune disease model experimental allergic encephalomyelitis (EAE). [Leu144, Arg147]-PLP (139-151 prevents EAE when co-administered with native PLP(139-151) and can limit progression of EAE if given early after the onset of disease in mice.
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Additional information
| Three Letter Sequence | H-His-Ser-Leu-Gly-Lys-Leu-Leu-Gly-Arg-Pro-Asp-Lys-Phe-OH |
|---|---|
| Molecular Weight | 1467.7 |
| Molecular Formula | C67H110N20O17 |
| Sequence | HSLGKLLGRPDKF |
| Solubility | Soluble in dilute acid |
| Appearance | Freeze dried solid |
| Storage | Store desiccated, frozen and in the dark |
| Purity | >95% by HPLC |
| Searchable Words | [Leu144, Arg147]-PLP (139-151), 188859-65-6, T-cell receptor antagonist, autoimmune disease model experimental allergic encephalomyelitis, EAE, H-HSLGKLLGRPDKF-OH, HSLGKLLGRPDKF, NR-040, NR040 |