[Leu144, Arg147]-PLP (139-151)

£75.00 1mg

T cell receptor antagonist.

[Leu144, Arg147]-PLP (139-151) is an analogue of PLP (139-151) which can act as a T-cell receptor antagonist, able to prevent development of the autoimmune disease model experimental allergic encephalomyelitis (EAE). [Leu144, Arg147]-PLP (139-151 prevents EAE when co-administered with native PLP(139-151) and can limit progression of EAE if given early after the onset of disease in mice.

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SKU: NR-040 Categories: ,

Additional information

Three Letter Sequence

H-His-Ser-Leu-Gly-Lys-Leu-Leu-Gly-Arg-Pro-Asp-Lys-Phe-OH

Molecular Weight

1467.7

Molecular Formula

C67H110N20O17

Sequence

HSLGKLLGRPDKF

Solubility

Soluble in dilute acid

Appearance

Freeze dried solid

Storage

Store desiccated, frozen and in the dark

Purity

>95% by HPLC

Searchable Words

[Leu144, Arg147]-PLP (139-151), 188859-65-6, T-cell receptor antagonist, autoimmune disease model experimental allergic encephalomyelitis, EAE, H-HSLGKLLGRPDKF-OH, HSLGKLLGRPDKF, NR-040, NR040