Kisspeptin 234

£85.00 1mg

Kisspeptin receptor antagonist.

Kisspeptin 234 is an analogue of kisspeptin 10 which acts as a kisspeptin receptor antagonist. Of a series, kisspeptin 234 most potently inhibited kisspeptin 10 stimulation of inositol phosphate release in Chinese hamster ovarian cells stably expressing the human GPR54 with an IC50 of 7 nM. Intracerebroventricular administration of kisspeptin 234 causes delayed vaginal opening in rats (an indicator of puberty) and prevents an increase in circulating luteinising hormone concentration when co-administrated with kisspeptin 10.

Please contact us for availability.

SKU: KR-010 Categories: ,

Additional information

Other Names

Peptide 234, p234, K234

Three Letter Sequence

Ac-(D)Ala-Asn-Trp-Asn-Gly-Phe-Gly-(D)Trp-Arg-Phe-NH2

Molecular Weight

1295.42

Molecular Formula

C63H78N18O13

Sequence

Ac-aNWNGFGwRF-NH2

Solubility

Soluble to 1 mg/ml in water

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Modifications

N-terminal acetyl, C-terminal amide; Ala-1 is D-Ala and Trp-8 is D-Trp

Searchable Words

Kisspeptin 234, 1145998-81-7, peptide 234, KR-010, KR010, Ac-aNWNGFGwRF-NH2, K234