Kisspeptin 10 (rat, mouse)
£89.00 1mg
Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.
Endogenous peptide for the rodent kisspeptin receptor KISS1 (GPR54).
Kisspeptin-10 is the endogenous ligand for the rodent kisspeptin receptor (KISS1, GPR54) and is the minimal sequence of metastin (45-54) which activates GPR54 signaling. Kisspeptin has recently emerged as a key regulator of the mammalian reproductive axis while stimulation of GPR54 can also up-regulate proapoptotic genes which have tumour suppressor properties, inhibiting metastasis and invasion in mouse melanomas.
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Additional information
| Three Letter Sequence | H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Tyr-NH2 |
|---|---|
| Molecular Weight | 1318.5 |
| Molecular Formula | C63H83N17O15 |
| Sequence | H-YNWNSFGLRY-NH2 |
| Solubility | Soluble in dilute acid |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and desiccated |
| Purity | >95% by HPLC |
| Modifications | C terminal amide |
| Searchable Words | Kisspeptin 10 (rat, mouse), H-YNWNSFGLRY-NH2, YNWNSFGLRY, 478507-53-8, Kisspeptin-10, kisspeptin receptor, KISS1, GPR54, metastin (45-54), metastasis, NR-060, NR060 |