From a technical viewpoint, the application of hPL, Human serum (HS) and FBS are very similar. hPL differs to sera products due to the increased volume of cytokines and growth factors contained within the product affecting the performance levels.
We would recommend the following paper by Bieback et al. 2009 that demonstrates the comparative performance difference between hPL, HS and FBS.
Bieback, K., et al. (2009) Human alternatives to fetal bovine serum for the expansion of mesenchymal stromal cells from bone marrow. Stem Cell, 27(9):2331-2341.