From a technical viewpoint, the preparation of hPL, Human serum (HS) and FBS are very similar. What differs is the performance levels for hPL, HS and FBS.
While different for hPL, HS and FBS, we do not have any in house data showing the performance levels of hPL compared with HS. However, we would recommend referring to the Bieback et al. 2009 paper, which shows the comparative performance difference between hPL, HS and FBS.
Bieback, K., et al. (2009) Human alternatives to fetal bovine serum for the expansion of mesenchymal stromal cells from bone marrow. Stem Cell, 27(9):2331-2341.