Histatin 5

£125.00 1mg

Antimicrobial peptide found in saliva.

Histatin 5 is a 24 amino acid histidine-rich cationic salivary peptide, formed with histatin 8 from post-translational cleavage of histatin 3. Histatins function as antimicrobial peptides and are important components of the innate immune system. Histatin 5 has broad spectrum antimicrobial action including activity against gram positive and gram negative bacteria, and fungi including Candida albicans and Aspergillus fumigans. Histatin 5 antifungal activity is caused by disruption to mitochondrial respiration through reactive oxygen species (ROS) production.

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SKU: AM-091 Categories: ,

Additional information

Three Letter Sequence

H-Asp-Ser-His-Ala-Lys-Arg-His-His-Gly-Tyr-Lys-Arg-Lys-Phe-His-Glu-Lys-His-His-Ser-His-Arg-Gly-Tyr-OH

Molecular Weight

3036.3

Molecular Formula

C133H195N51O33

Sequence

DSHAKRHHGYKRKFHEKHHSHRGY

Solubility

Soluble in dilute acid

Appearance

Freeze dried solid

Storage

Store desiccated, frozen and in the dark

Purity

>95% by HPLC

Searchable Words

H-DSHAKRHHGYKRKFHEKHHSHRGY-OH, DSHAKRHHGYKRKFHEKHHSHRGY, 104339-66-4, Histatin 5, innate immune system, antimicrobial, AM-091, AM091