Histatin 5
£125.00 1mg
Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.
Antimicrobial peptide found in saliva.
Histatin 5 is a 24 amino acid histidine-rich cationic salivary peptide, formed with histatin 8 from post-translational cleavage of histatin 3. Histatins function as antimicrobial peptides and are important components of the innate immune system. Histatin 5 has broad spectrum antimicrobial action including activity against gram positive and gram negative bacteria, and fungi including Candida albicans and Aspergillus fumigans. Histatin 5 antifungal activity is caused by disruption to mitochondrial respiration through reactive oxygen species (ROS) production.
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Additional information
| Three Letter Sequence | H-Asp-Ser-His-Ala-Lys-Arg-His-His-Gly-Tyr-Lys-Arg-Lys-Phe-His-Glu-Lys-His-His-Ser-His-Arg-Gly-Tyr-OH |
|---|---|
| Molecular Weight | 3036.3 |
| Molecular Formula | C133H195N51O33 |
| Sequence | DSHAKRHHGYKRKFHEKHHSHRGY |
| Solubility | Soluble in dilute acid |
| Appearance | Freeze dried solid |
| Storage | Store desiccated, frozen and in the dark |
| Purity | >95% by HPLC |
| Searchable Words | H-DSHAKRHHGYKRKFHEKHHSHRGY-OH, DSHAKRHHGYKRKFHEKHHSHRGY, 104339-66-4, Histatin 5, innate immune system, antimicrobial, AM-091, AM091 |