Foxy 5
£85.00 1mg
Wnt5a mimetic peptide.
Foxy 5 is a formylated hexapeptide derived from the sequence of the Wnt5a ligand which acts as a Wnt5a mimetic. Foxy 5 is able to mimic important effects exerted by the full Wnt5a molecule such as binding to the Frz-5 receptor, and reproducing Wnt5a-induced inhibition of human breast cancer cell migration in vitro. Foxy 5 significantly reduces the metastatic spread of WNT5a ?low DU145 prostate cancer cells in an in vivo orthotopic xenograft mouse model.
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Additional information
| Other Names | Wnt5a hexapeptide, Foxy5 |
|---|---|
| Three Letter Sequence | N-Formyl-Met-Asp-Gly-Cys-Glu-Leu-OH |
| Molecular Weight | 694.77 |
| Molecular Formula | C26H42N6O12S2 |
| Sequence | N-Formyl-MDGCEL |
| Solublity | Soluble to 1 mg/ml in PBS |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| Purity | >95% by HPLC |
| Modifications | N-Formylated |
| Searchable Words | Foxy 5, 881188-51-8, N-Formyl-MDGCEL, PP-110, Foxy5, Foxy-5 |