Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

Inactivates HIV-1 virions.

F9170 is a peptide identified from the cytoplasmic region of the HIV-1 envelope glycoprotein (Env, gp120-gp41) which is able to inactivate HIV-1 virions and induce necrosis of HIV-1 infected cells. F9170 can enter the brain and lymph nodes and specifically targets the conserved cytoplasmic tail of HIV-1 Env to disrupt the integrity of the viral membrane. F9170 short-term administration can control viral loads to below the limit of detection in chronically SHIV infected macaques.

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