F9170

£125.00 1mg

Inactivates HIV-1 virions.

F9170 is a peptide identified from the cytoplasmic region of the HIV-1 envelope glycoprotein (Env, gp120-gp41) which is able to inactivate HIV-1 virions and induce necrosis of HIV-1 infected cells. F9170 can enter the brain and lymph nodes and specifically targets the conserved cytoplasmic tail of HIV-1 Env to disrupt the integrity of the viral membrane. F9170 short-term administration can control viral loads to below the limit of detection in chronically SHIV infected macaques.

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SKU: AV-010 Categories: ,

Additional information

Three Letter Sequence

H-Gly-Trp-Glu-Ala-Leu-Lys-Tyr-Leu-Trp-Asn-Leu-Leu-Gln-Tyr-Trp-OH

Molecular Weight

1983.3

Molecular Formula

C100H135N21O22

Sequence

GWEALKYLWNLLQYW

Solubility

Soluble in water

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Searchable Words

F9170, F 9170, AV-010, AV010, GWEALKYLWNLLQYW