Endomorphin-2
£55.00 5mg
Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.
Potent and selective μ opioid receptor agonist.
Endomorphin-2 is an endogenous peptide with extremely high affinity and selectivity for μ-opioid receptors, with Ki values of 0.69, 9233 and 5240 nM for μ, δ and κ receptors respectively. Endomorphin-2 is one of the two endomorphins and along with endomorphin-1 produces analgesia in animals, but whereas endomorphin-1 is more prevalent in the brain, endomorphin-2 is more prevalent in the spinal cord.
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Additional information
Other Names | EM-2 |
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Three Letter Sequence | H-Tyr-Pro-Phe-Phe-NH2 |
Molecular Weight | 571.65 |
Molecular Formula | C32H37N5O5 |
Sequence | YPFF-NH2 |
Solubility | Soluble to 0.40 mg/ml in water |
Appearance | Freeze dried solid |
Storage | Store dry, frozen and in the dark |
Purity | >95% by HPLC |
Modifications | C-terminal amide |
Searchable Words | Endomorphin-2, Endomorphin-2, Endomorphin2, 141801-26-5, EM-2, H-Tyr-Pro-Phe-Phe-NH2 |