Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

Endogenous kappa receptor agonist.

Dynorphins are a class of opioid peptides that arise from the precursor protein prodynorphin, which when cleaved by proprotein convertase 2, releases multiple active peptides including dynorphin A, dynorphin B, and ?/?-neo-endorphin. Dynorphin A is an endogenous kappa receptor agonist and has different physiological actions depending upon its site of production. Dynorphin A is a modulator of pain responses and also has roles in weight control, regulating body temperature, and influencing drug seeking behaviour.

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