Cys-Pexiganan

£175.00 1mg

The broad-spectrum antibacterial pexiganan with an additional N-terminal cysteine.

Cys-Pexiganan is the broad-spectrum antibacterial pexiganan with an additional N-terminal cysteine attached. Pexiganan is a 22-amino acid analog of the naturally occurring antimicrobial magainin2 , extracted from the skin of the African frog Xenopus laevis. Pexiganan exhibits in vitro broad-spectrum antibacterial activity against many clinical isolates of gram-positive and gram-negative, anaerobic and aerobic bacteria and is the best-studied AMP to date for therapeutic purposes. The addition of the N-terminal cysteine in Cys-pexiganan allows immobilization of pexiganan as a novel approach towards endowing material surfaces with bactericidal properties as well as attachment of fluorescent or biotin tags.

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SKU: AM-230 Categories: ,

Additional information

Three Letter Sequence

H-Cys-Gly-Ile-Gly-Lys-Phe-Leu-Lys-Lys-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Lys-Ile-Leu-Lys-Lys-NH2

Molecular Weight

2580.35

Molecular Formula

C125H215N33O23S

Sequence

CGIGKFLKKAKKFGKAFVKILKK-NH2

Solubility

Soluble in water

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Modifications

C terminal amide

Searchable Words

Cys-Pexiganan, antibacterial, additional N-terminal cysteine, Pexiganan , H-CGIGKFLKKAKKFGKAFVKILKK-NH2, CGIGKFLKKAKKFGKAFVKILKK-NH2, AM-230, AM230