[cPP1-7,NPY19-23,Ala31,Aib32,Gln34] – hPancreatic polypeptide

£175.00 1mg

Potent and selective Y5 agonist.

[cPP1-7,NPY19-23,Ala31,Aib32,Gln34] – hPancreatic Polypeptide is a potent and selective peptide agonist for the neuropeptide Y Y5 receptor , with IC50 values for inhibition of neuropeptide Y binding to human Y5, Y1, Y2 and Y4 receptors of 0.24, 530, > 500, and 51 nM respectively, and a Ki at Y5 of  0.1 – 0.15 nM. [cPP1-7,NPY19-23,Ala31,Aib32,Gln34] – hPancreatic Polypeptide stimulates food intake in vivo.

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SKU: NY-010 Categories: ,

Additional information

Other Names

[cPP1 “7,NPY19 “23,Ala31,Aib32,Gln34]hPP

Three Letter Sequence

H-Gly-Pro-Ser-Gln-Pro-Thr-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Ala-Aib-Arg-Gln-Arg-Tyr-NH2

Molecular Weight

4207.67

Molecular Formula

C183H281N57O54S2

Sequence

GPSQPTYPGDNATPEQMARYYSALRRYINMAXRQRY-NH2

Solubility

Soluble to 1 mg/ml in water

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Modifications

X = Aib, Tyr-36 = C-terminal amide

Searchable Words

GPSQPTYPGDNATPEQMARYYSALRRYINMAXRQRY-NH2, GPSQPTYPGDNATPEQMARYYSALRRYINMAXRQRY, 313988-89-5, [cPP1-7,NPY19-23,Ala31,Aib32,Gln34] – hPancreatic Polypeptide, [cPP1 “7,NPY19 “23,Ala31,Aib32,Gln34]hPP, GPSQPTYPGDNATPEQMARYYSALRRYINMABRQRY-NH2