Bombesin

£55.00 1mg

Endogenous mammalian neurotransmitter which activates bombesin receptors (BBR) 1, -2, and -3.

Bombesin is a 14 amino acid endogenous mammalian neurotransmitter which activates three different G-protein-coupled receptors, bombesin receptor (BBR) 1, -2, and -3. Bombesin exhibits many biological effects including hormone release, stimulation of pancreatic enzyme secretion, inhibition of gastric emptying and modulation of gastric acid secretion. Bombesin also activates these receptors in the brain and together with cholecystokinin, it is the second major source of negative feedback signals that stop eating behaviour. Bombesin is also a tumour marker for small cell lung carcinoma, gastric cancer, pancreatic cancer, and neuroblastoma.

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SKU: NR-150 Categories: ,

Additional information

Three Letter Sequence

pGlu-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2

Molecular Weight

1619.9

Molecular Formula

C71H110N24O18S

Sequence

XQRLGNQWAVGHLM-NH2

Solubility

Soluble in dilute acid

Appearance

Freeze dried solid

Storage

Store dark, frozen and desiccated

Purity

>95% by HPLC

Modifications

X is pGlu, C terminal amide

Searchable Words

31362-50-2, Bombesin, pGlu-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2, NR-150, NR150,