BMP-2 Derived Peptide
£145.00 1mg
Inhibits BMP-2 binding to BMP receptors type IA and type II.
BMP-2 derived peptide, also known as bone morphogenetic protein 2 (BMP-2) derived peptide, corresponds to residues 73-92 of the knuckle epitope of BMP-2. BMP-2 derived peptide significantly inhibits the binding of recombinant human BMP-2 to both BMP receptors type IA and type II and also promotes the expression of osteocalcin mRNA and induces ectopic calcification in rat calf muscle. BMP-2 derived peptide may one of the receptor binding sites on BMP-2 and may stimulate bone precursor cells to induce calcification. The sequence lacking the GGC linker at the C teminal, BMP2pp is also available.
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Additional information
| Other Names | Bone morphogenetic protein 2 derived peptide |
|---|---|
| Three Letter Sequence | H-Lys-Ile-Pro-Lys-Ala-Ser-Ser-Val-Pro-Thr-Glu-Leu-Ser-Ala-Ile-Ser-Thr-Leu-Tyr-Leu-Gly-Gly-Cys-NH2 |
| Molecular Weight | 2334.76 |
| Molecular Formula | C104H176N26O32S |
| Sequence | KIPKASSVPTELSAISTLYLGGC-NH2 |
| Solubility | Soluble in water |
| Appearance | Freeze dried solid |
| Storage | Store desiccated, frozen and in the dark |
| Purity | >95% by HPLC |
| Modifications | C terminal amide |
| Searchable Words | BMP-2 derived peptide, Bone morphogenetic protein 2, BMP-2, peptide, residues 73-92, epitope, BMP receptors, type IA, type II, osteogenesis, H-KIPKASSVPTELSAISTLYLGGC-NH2, KIPKASSVPTELSAISTLYLGGC, EI-030, EI030 |