BMP-2 derived peptide
£145.00 1mg
Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.
Inhibits BMP-2 binding to BMP receptors type IA and type II.
BMP-2 derived peptide, also known as bone morphogenetic protein 2 (BMP-2) derived peptide, corresponds to residues 73-92 of the knuckle epitope of BMP-2. BMP-2 derived peptide significantly inhibits the binding of recombinant human BMP-2 to both BMP receptors type IA and type II and also promotes the expression of osteocalcin mRNA and induces ectopic calcification in rat calf muscle. BMP-2 derived peptide may one of the receptor binding sites on BMP-2 and may stimulate bone precursor cells to induce calcification. The sequence lacking the GGC linker at the C teminal, BMP2pp is also available.
Please contact us for availability.
Additional information
| Other Names | Bone morphogenetic protein 2 derived peptide |
|---|---|
| Three Letter Sequence | H-Lys-Ile-Pro-Lys-Ala-Ser-Ser-Val-Pro-Thr-Glu-Leu-Ser-Ala-Ile-Ser-Thr-Leu-Tyr-Leu-Gly-Gly-Cys-NH2 |
| Molecular Weight | 2334.76 |
| Molecular Formula | C104H176N26O32S |
| Sequence | KIPKASSVPTELSAISTLYLGGC-NH2 |
| Solubility | Soluble in water |
| Appearance | Freeze dried solid |
| Storage | Store desiccated, frozen and in the dark |
| Purity | >95% by HPLC |
| Modifications | C terminal amide |
| Searchable Words | BMP-2 derived peptide, Bone morphogenetic protein 2, BMP-2, peptide, residues 73-92, epitope, BMP receptors, type IA, type II, osteogenesis, H-KIPKASSVPTELSAISTLYLGGC-NH2, KIPKASSVPTELSAISTLYLGGC, EI-030, EI030 |