BMP-2 Derived Peptide

£145.00 1mg

Inhibits BMP-2 binding to BMP receptors type IA and type II.

BMP-2 derived peptide, also known as bone morphogenetic protein 2 (BMP-2) derived peptide, corresponds to residues 73-92 of the knuckle epitope of BMP-2. BMP-2 derived peptide significantly inhibits the binding of recombinant human BMP-2 to both BMP receptors type IA and type II and also promotes the expression of osteocalcin mRNA and induces ectopic calcification in rat calf muscle. BMP-2 derived peptide may one of the receptor binding sites on BMP-2 and may stimulate bone precursor cells to induce calcification. The sequence lacking the GGC linker at the C teminal, BMP2pp is also available.

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SKU: EI-030 Categories: ,

Additional information

Other Names

Bone morphogenetic protein 2 derived peptide

Three Letter Sequence

H-Lys-Ile-Pro-Lys-Ala-Ser-Ser-Val-Pro-Thr-Glu-Leu-Ser-Ala-Ile-Ser-Thr-Leu-Tyr-Leu-Gly-Gly-Cys-NH2

Molecular Weight

2334.76

Molecular Formula

C104H176N26O32S

Sequence

KIPKASSVPTELSAISTLYLGGC-NH2

Solubility

Soluble in water

Appearance

Freeze dried solid

Storage

Store desiccated, frozen and in the dark

Purity

>95% by HPLC

Modifications

C terminal amide

Searchable Words

BMP-2 derived peptide, Bone morphogenetic protein 2, BMP-2, peptide, residues 73-92, epitope, BMP receptors, type IA, type II, osteogenesis, H-KIPKASSVPTELSAISTLYLGGC-NH2, KIPKASSVPTELSAISTLYLGGC, EI-030, EI030