BING

£125.00 1mg

Antimicrobial peptide isolated from Japanese medaka fish.

BING is an antimicrobial peptide found in the plasma of the Japanese rice fish medaka (Oryzias latipes), derived from vacuolar protein sorting-associated protein 13D-like (Vps13D). BING possesses toxicity against a broad range of gram-positive and negative bacteria including drug resistant strains, at concentrations that have low toxicity to mammalian cell lines. BING treatment induces deregulation of periplasmic peptidyl-prolyl isomerases in gram-negative bacteria and also reduces the RNA level of cpxR, an upstream regulator of envelope stress responses which plays a crucial role in the development of antimicrobial resistance.

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SKU: AM-280 Categories: ,

Additional information

Other Names

Blocker of INter-membrane stress responses of Gram-negative bacteria

Three Letter Sequence

H-Ile-Arg-Ile-Ile-Leu-Arg-Ala-Gln-Gly-Ala-Leu-Lys-Ile-OH

Molecular Weight

1464.86

Molecular Formula

C67H125N21O15

Sequence

IRIILRAQGALKI

Solublity

Soluble in water

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Searchable Words

BING, IRIILRAQGALKI, AM280, AM-280