Bim BH3
£95.00 1mg
Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.
BH3 only protein Bim fragment.
Bim BH3 is a 26-residue fragment from the BH3 only protein Bim. BH3 only proteins are pro-apoptotic members of the B-cell lymphoma 2 (Bcl-2) family of apoptotic regulatory proteins and participate in embryonic development, tissue homeostasis and immunity. The mammalian BH3-only proteins include Bad, Bid, Bik/NBK, Bim/Bod, Bmf, Hrk/DP5, Noxa and Puma/BBC3. ? Bim BH3 binds to Bcl-2, Bcl-xL and Mcl-1 with very high affinity.
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Additional information
| Other Names | Peptide IV, Bim BH3 peptide |
|---|---|
| Three Letter Sequence | H-Asp-Met-Arg-Pro-Glu-Ile-Trp-Ile-Ala-Gln-Glu-Leu-Arg-Arg-Ile-Gly-Asp-Glu-Phe-Asn-Ala-Tyr-Tyr-Ala-Arg-Arg-OH |
| Molecular Weight | 3269.69 |
| Molecular Formula | C145H222N44O41S |
| Sequence | DMRPEIWIAQELRRIGDEFNAYYARR |
| Solubility | Soluble in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| Purity | >95% by HPLC |
| Searchable Words | Bim BH3, Peptide IV, DMRPEIWIAQELRRIGDEFNAYYARR, PP-070 |