BigLEN (mouse)
£85.00 1mg
Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.
Endogenous GPR171 agonist.
BigLEN (mouse) is a neuropeptide that is derived from the precursor peptide ProSAAS and is the endogenous agonist for the previously orphaned GPR171 receptor. BigLEN (mouse) is one of the most abundant neuropeptides in the brain, and it modulates feeding-related behaviours within the hypothalamus. The BigLEN-GPR171 system is widely expressed in the basolateral amygdala (BLA) and has also been shown to have an important role in the pathology of anxiety and mood disorders.
Additional information
| Three Letter Sequence | H-Leu-Glu-Asn-Pro-Ser-Pro-Gln-Ala-Pro-Ala-Arg-Arg-Leu-Leu-Pro-Pro-OH |
|---|---|
| Molecular Weight | 1756.03 |
| Molecular Formula | C78H130N24O22 |
| Sequence | LENPSPQAPARRLLPP |
| Solubility | Soluble to 2 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| Purity | >95% by HPLC |
| Searchable Words | BigLEN (mouse), GP-010, 501036-69-7, LENPSPQAPARRLLPP |