BAM 22P
£125.00 1mg
Endogenous MRGPRX1 agonist.
BAM 22P is a potent endogenous agonist, derived from the proenkephalin A gene, for the Mas-related G protein-coupled receptor X1 (MRGPRX1), which was originally isolated from bovine adrenal medulla. BAM 22P is a potent opioid agonist with an IC50 of 1.3 nM in guinea pig ileum. BAM 22P can produces opioid- and non-opioid receptor mediated antinociceptive effects in vivo.
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Additional information
| Three Letter Sequence | H-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-Gly-Arg-Pro-Glu-Trp-Trp-Met-Asp-Tyr-Gln-Lys-Arg-Tyr-Gly-OH |
|---|---|
| Molecular Weight | 2839.2 |
| Molecular Formula | C130H184N38O31S2 |
| Sequence | YGGFMRRVGRPEWWMDYQKRYG |
| Solubility | Soluble to 1 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store desiccated, frozen and in the dark |
| Purity | >95% by HPLC |
| Searchable Words | PN-110, BAM 22P, proenkephalin A gene, Mas-related G protein-coupled receptor X1, MRGPRX1, bovine adrenal medulla, antinociceptive , H-YGGFMRRVGRPEWWMDYQKRYG-OH, YGGFMRRVGRPEWWMDYQKRYG, 76622-26-9, PN-110, PN110 |