BAM 22P
£125.00 1mg
Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.
Endogenous MRGPRX1 agonist.
BAM 22P is a potent endogenous agonist, derived from the proenkephalin A gene, for the Mas-related G protein-coupled receptor X1 (MRGPRX1), which was originally isolated from bovine adrenal medulla. BAM 22P is a potent opioid agonist with an IC50 of 1.3 nM in guinea pig ileum. BAM 22P can produces opioid- and non-opioid receptor mediated antinociceptive effects in vivo.
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Additional information
| Three Letter Sequence | H-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-Gly-Arg-Pro-Glu-Trp-Trp-Met-Asp-Tyr-Gln-Lys-Arg-Tyr-Gly-OH |
|---|---|
| Molecular Weight | 2839.2 |
| Molecular Formula | C130H184N38O31S2 |
| Sequence | YGGFMRRVGRPEWWMDYQKRYG |
| Solubility | Soluble to 1 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store desiccated, frozen and in the dark |
| Purity | >95% by HPLC |
| Searchable Words | PN-110, BAM 22P, proenkephalin A gene, Mas-related G protein-coupled receptor X1, MRGPRX1, bovine adrenal medulla, antinociceptive , H-YGGFMRRVGRPEWWMDYQKRYG-OH, YGGFMRRVGRPEWWMDYQKRYG, 76622-26-9, PN-110, PN110 |