Autocamtide-2-related inhibitory peptide
£125.00 1mg
Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.
CaM kinase II inhibitor.
Autocamtide-2-related inhibitory peptide is a selective and potent calmodulin-dependent protein kinase II (CaM kinase II) inhibitor with an IC50 of 40 nM. Autocamtide-2-related inhibitory peptide is selective over PKC, PKA and CaM kinase IV, with IC50’s greater than 10 μM for each. Autocamtide 2 related inhibitory peptide reverses CaMKII mediated effects in cardiac channels but does not alter INa gating.
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Additional information
| Other Names | AIP |
|---|---|
| Three Letter Sequence | H-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH |
| Molecular Weight | 1497.76 |
| Molecular Formula | C64H116N22O19 |
| Sequence | KKALRRQEAVDAL |
| Solubility | Soluble to 1 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| Purity | >95% by HPLC |
| Searchable Words | Autocamtide-2-related inhibitory peptide, KKALRRQEAVDAL, 167114-91-2, AIP, KS-190, KS190, KS 190 |