Autocamtide-2-related inhibitory peptide
£125.00 1mg
CaM kinase II inhibitor.
Autocamtide-2-related inhibitory peptide is a selective and potent calmodulin-dependent protein kinase II (CaM kinase II) inhibitor with an IC50 of 40 nM. Autocamtide-2-related inhibitory peptide is selective over PKC, PKA and CaM kinase IV, with IC50’s greater than 10 μM for each. Autocamtide 2 related inhibitory peptide reverses CaMKII mediated effects in cardiac channels but does not alter INa gating.
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Additional information
| Other Names | AIP |
|---|---|
| Three Letter Sequence | H-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH |
| Molecular Weight | 1497.76 |
| Molecular Formula | C64H116N22O19 |
| Sequence | KKALRRQEAVDAL |
| Solubility | Soluble to 1 mg/ml in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| Purity | >95% by HPLC |
| Searchable Words | Autocamtide-2-related inhibitory peptide, KKALRRQEAVDAL, 167114-91-2, AIP, KS-190, KS190, KS 190 |