Apelin 12

£55.00 1mg

C-terminal fragment of the 77 amino acid prepropeptide apelin.

Apelin 12 (A12) is a biologically active C-terminal fragment of the 77 amino acid prepropeptide apelin, which is also the precursor of apelin 13 and apelin 36. Apelin 12 lowers blood pressure via a nitric oxide-dependent mechanism and is involved in control of feeding through stimulation of cholecystokinin (CCK) secretion. Apelin 12 can also reduce infarct size (IS) and augment contractile function recovery in the heart of rodents after regional or global ischemia.

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SKU: CS-020 Categories: ,

Additional information

Other Names

A12

Three Letter Sequence

H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-OH

Molecular Weight

1422.7

Molecular Formula

C64H103N21O14S

Sequence

RPRLSHKGPMPF

Solubility

Soluble in physiological buffers including PBS (>1mg./mL). Soluble in DMSO as a stock solution.

Appearance

Freeze dried solid

Storage

Store dessicated, frozen and in the dark

Purity

>95% by HPLC

Searchable Words

H-RPRLSHKGPMPF-OH, RPRLSHKGPMPF, 229961-08-4, Apelin 12, A12, C-terminal fragment, apelin, CS-020, CS020