Home » Shop All Products » Antibodies » Peptides » Other Peptides
[Ala11,D-Leu15]-Orexin B

[Ala11,D-Leu15]-Orexin B

£125.00 1mg

SKU: OX-040 Categories: , ,

Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

Potent and selective orexin2 receptor agonist.

[Ala11,D-Leu15]-Orexin B is a highly potent and selective OX2 receptor agonist with 400-fold selectivity for OX2 over OX1 receptors, possessing EC50 values of 0.13 and 52 nM for human OX2 and OX1 receptors respectively. [Ala11,D-Leu15]-Orexin B increases social novelty seeking and can decrease anxious and depressive behaviour in animal models.

Please contact us for availability.

Additional information

Other Names

[Ala(11), D-Leu(15)]orexin-B, [Ala11, d-Leu15] “OrxB
Three Letter Sequence

H-Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Ala-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
Molecular Weight

2857.28
Molecular Formula

C189H284N54O56S
Sequence

RSGPPGLQGRAQRLLQASGNHAAGILTM-NH2
Solubility

Soluble to 0.30 mg/ml in water
Appearance

Freeze dried solid
Storage

Store dry, frozen and in the dark
Purity

>95% by HPLC
Modifications

C-terminal amide
Searchable Words

[Ala11,D-Leu15]-Orexin B, 532932-99-3, RSGPPGLQGRAQRLLQASGNHAAGILTM, RSGPPGLQGRAQRLLQASGNHAAGILTM-NH2, [Ala(11), D-Leu(15)]orexin-B, OX-040, OX040