Ac2-26

£185.00 1mg

Annexin/lipocortin 1 mimetic.

Ac2-26 is the N terminal fragment of annexin A1 and an annexin/lipocortin 1 mimetic. Ac2-26 can inhibit leukocyte extravasation, reduce neutrophil adhesion and emigration, promote detachment of neutrophils from activated mesenteric endothelium and accelerate epithelial wound repair. Local intestinal delivery of Ac2-26 encapsulated within targeted polymeric nanoparticles accelerates healing of murine colonic wounds after biopsy-induced injury.

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SKU: PP-100 Categories: ,

Additional information

Other Names

AnxA1 mimetic peptide, Lipocortin-1 (2-26), Annexin-1 (2-26) (human)

Three Letter Sequence

Ac-Ala-Met-Val-Ser-Glu-Phe-Leu-Lys-Gln-Ala-Trp-Phe-Ile-Glu-Asn-Glu-Glu-Gln-Glu-Tyr-Val-Gln-Thr-Val-Lys-OH

Molecular Weight

3089.46

Molecular Formula

C141H210N32O44S

Sequence

Ac-AMVSEFLKQAWFIENEEQEYVQTVK

Solubility

Soluble to 1 mg/ml in phosphate buffered saline

Appearance

Freeze dried solid

Storage

Store dry, frozen and in the dark

Purity

>95% by HPLC

Modifications

N terminal acetyl

Searchable Words

Ac2-26 , 151988-33-9, AcAMVSEFLKQAWFIENEEQEYVQTVK , AMVSEFLKQAWFIENEEQEYVQTVK , Lipocortin-1 (2-26) / Annexin-1 (2-26) (Human), PP-100