Ac2-26
£185.00 1mg
Annexin/lipocortin 1 mimetic.
Ac2-26 is the N terminal fragment of annexin A1 and an annexin/lipocortin 1 mimetic. Ac2-26 can inhibit leukocyte extravasation, reduce neutrophil adhesion and emigration, promote detachment of neutrophils from activated mesenteric endothelium and accelerate epithelial wound repair. Local intestinal delivery of Ac2-26 encapsulated within targeted polymeric nanoparticles accelerates healing of murine colonic wounds after biopsy-induced injury.
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Additional information
| Other Names | AnxA1 mimetic peptide, Lipocortin-1 (2-26), Annexin-1 (2-26) (human) |
|---|---|
| Three Letter Sequence | Ac-Ala-Met-Val-Ser-Glu-Phe-Leu-Lys-Gln-Ala-Trp-Phe-Ile-Glu-Asn-Glu-Glu-Gln-Glu-Tyr-Val-Gln-Thr-Val-Lys-OH |
| Molecular Weight | 3089.46 |
| Molecular Formula | C141H210N32O44S |
| Sequence | Ac-AMVSEFLKQAWFIENEEQEYVQTVK |
| Solubility | Soluble to 1 mg/ml in phosphate buffered saline |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
| Purity | >95% by HPLC |
| Modifications | N terminal acetyl |
| Searchable Words | Ac2-26 , 151988-33-9, AcAMVSEFLKQAWFIENEEQEYVQTVK , AMVSEFLKQAWFIENEEQEYVQTVK , Lipocortin-1 (2-26) / Annexin-1 (2-26) (Human), PP-100 |