A20FMDV2

£125.00 1mg

Selective alpha-v beta-6 (v6) integrin antagonist.

A20FMDV2 is a peptide derived from the foot-and-mouth disease virus with a high affinity and selectivity for the alpha-v beta-6 (v6) arginyl-glycinyl-aspartic acid (RGD)-binding integrin, inhibiting alphavbeta6-ligand binding with a IC50 of 3 nmol/L, an activity 1,000-fold more selective for alphavbeta6 than for other RGD-directed integrins (alphavbeta3, alphavbeta5, and alpha5beta1).

SKU: IG-010 Categories: ,

Additional information

Three Letter Sequence

H-Asn-Ala-Val-Pro-Asn-Leu-Arg-Gly-Asp-Leu-Gln-Val-Leu-Ala-Gln-Lys-Val-Ala-Arg-Thr-NH2

Molecular Weight

2162.5

Molecular Formula

C93H164N32O27

Sequence

NAVPNLRGDLQVLAQKVART-NH2

Solubility

Soluble in water

Appearance

Freeze dried solid

Storage

We recommend storage desiccated, frozen and in the dark

Purity

>95% by HPLC

Modifications

C terminal amide

Searchable Words

A20FMDV2, 932699-03-1, H-NAVPNLRGDLQVLAQKVART-NH2, NAVPNLRGDLQVLAQKVART, foot-and-mouth, alpha-v beta-6, ?v?6, arginyl-glycinyl-aspartic acid, IG-010, IG010