A20FMDV2
£125.00 1mg
Selective alpha-v beta-6 (v6) integrin antagonist.
A20FMDV2 is a peptide derived from the foot-and-mouth disease virus with a high affinity and selectivity for the alpha-v beta-6 (v6) arginyl-glycinyl-aspartic acid (RGD)-binding integrin, inhibiting alphavbeta6-ligand binding with a IC50 of 3 nmol/L, an activity 1,000-fold more selective for alphavbeta6 than for other RGD-directed integrins (alphavbeta3, alphavbeta5, and alpha5beta1).
Additional information
| Three Letter Sequence | H-Asn-Ala-Val-Pro-Asn-Leu-Arg-Gly-Asp-Leu-Gln-Val-Leu-Ala-Gln-Lys-Val-Ala-Arg-Thr-NH2 |
|---|---|
| Molecular Weight | 2162.5 |
| Molecular Formula | C93H164N32O27 |
| Sequence | NAVPNLRGDLQVLAQKVART-NH2 |
| Solubility | Soluble in water |
| Appearance | Freeze dried solid |
| Storage | We recommend storage desiccated, frozen and in the dark |
| Purity | >95% by HPLC |
| Modifications | C terminal amide |
| Searchable Words | A20FMDV2, 932699-03-1, H-NAVPNLRGDLQVLAQKVART-NH2, NAVPNLRGDLQVLAQKVART, foot-and-mouth, alpha-v beta-6, ?v?6, arginyl-glycinyl-aspartic acid, IG-010, IG010 |