736-745-TAT
£145.00 1mg
Inhibits the interaction of TRPV1 and AKAP79.
736-745-TAT, also known as TAT-TRPV1(736-745), is a cell permeable TRPV1 fragment that can inhibit the interaction of TRPV1 and AKAP79. 736-745-TAT consists of amino acids 736-749 from the TRPV1 C-terminal domain, combined with amino acids 47 57 of TAT to promote uptake across neuronal cell membranes. 736-745-TAT inhibits both the first and the second phase of pain behaviour in the formalin test, implying an effect on both acute and inflammatory pain.
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Additional information
| Other Names | TAT-TRPV1(736-745) |
|---|---|
| Three Letter Sequence | H-Lys-Asp-Asp-Tyr-Arg-Trp-Cys-Phe-Arg-Val-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-OH |
| Molecular Weight | 2929.41 |
| Molecular Formula | C127H206N50O29S1 |
| Sequence | KDDYRWCFRVYGRKKRRQRRR |
| Solubility | Soluble in DMSO |
| Appearance | Freeze dried solid |
| Storage | Store desiccated, frozen and in the dark |
| Purity | >95% by HPLC |
| Searchable Words | KDDYRWCFRVYGRKKRRQRRR, 736-745-TAT, aTAT-TRPV1(736-745), TRPV1, AKAP79, pain, PP-160 |