736-745-TAT

£145.00 1mg

Inhibits the interaction of TRPV1 and AKAP79.

736-745-TAT, also known as TAT-TRPV1(736-745), is a cell permeable TRPV1 fragment that can inhibit the interaction of TRPV1 and AKAP79. 736-745-TAT consists of amino acids 736-749 from the TRPV1 C-terminal domain, combined with amino acids 47 57 of TAT to promote uptake across neuronal cell membranes. 736-745-TAT inhibits both the first and the second phase of pain behaviour in the formalin test, implying an effect on both acute and inflammatory pain.

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SKU: PP-160 Categories: ,

Additional information

Other Names

TAT-TRPV1(736-745)

Three Letter Sequence

H-Lys-Asp-Asp-Tyr-Arg-Trp-Cys-Phe-Arg-Val-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-OH

Molecular Weight

2929.41

Molecular Formula

C127H206N50O29S1

Sequence

KDDYRWCFRVYGRKKRRQRRR

Solubility

Soluble in DMSO

Appearance

Freeze dried solid

Storage

Store desiccated, frozen and in the dark

Purity

>95% by HPLC

Searchable Words

KDDYRWCFRVYGRKKRRQRRR, 736-745-TAT, aTAT-TRPV1(736-745), TRPV1, AKAP79, pain, PP-160